Protein Surface Recognition Approaches for Drug Discovery

Protein Surface Recognition Approaches for Drug Discovery

❰Epub❯ ➛ Protein Surface Recognition Approaches for Drug Discovery Author Ernest Giralt – Anglo-saxon.co A new perspective on the design of molecular therapeutics is emerging This new strategy emphasizes the rational complementation of functionality along extended patches of a protein surface with the aiA new perspective on the design of molecular therapeutics is emerging This new strategy emphasizes the rational complementation of functionality along extended patches of a protein surface with the aim of inhibiting proteinprotein interactions The successful development of compounds able to inhibit these interactions offers a unique chance to selectively intervene in a large number of key cellular processes related to human diseaseProtein Surface Recognition presents a detailed treatment of this strategy with topics including an extended survey of protein protein interactions that are key players in human disease and biology and the potential for therapeutics derived from this new perspective the fundamental physical issues that surround protein protein interactions that must be considered when designing ligands for protein surfaces examples of protein surface small molecule interactions including treatments of protein natural product interactions protein interface peptides and rational approaches to protein surface recognition from model to biological systems a survey of techniques that will be integral to the discovery of new small molecule protein surface binders from high throughput synthesis and screening techniques to in silico and in vitro methods for the discovery of novel protein ligandsProtein Surface Recognition provides an intellectual tool kit for investigators in medicinal and bioorganic chemistry looking to exploit this emerging paradigm in drug discovery.

protein kindle surface download recognition free approaches download drug mobile discovery free Protein Surface book Recognition Approaches download Recognition Approaches for Drug pdf Surface Recognition Approaches epub Surface Recognition Approaches for Drug free Protein Surface Recognition Approaches for Drug Discovery ePUBA new perspective on the design of molecular therapeutics is emerging This new strategy emphasizes the rational complementation of functionality along extended patches of a protein surface with the aim of inhibiting proteinprotein interactions The successful development of compounds able to inhibit these interactions offers a unique chance to selectively intervene in a large number of key cellular processes related to human diseaseProtein Surface Recognition presents a detailed treatment of this strategy with topics including an extended survey of protein protein interactions that are key players in human disease and biology and the potential for therapeutics derived from this new perspective the fundamental physical issues that surround protein protein interactions that must be considered when designing ligands for protein surfaces examples of protein surface small molecule interactions including treatments of protein natural product interactions protein interface peptides and rational approaches to protein surface recognition from model to biological systems a survey of techniques that will be integral to the discovery of new small molecule protein surface binders from high throughput synthesis and screening techniques to in silico and in vitro methods for the discovery of novel protein ligandsProtein Surface Recognition provides an intellectual tool kit for investigators in medicinal and bioorganic chemistry looking to exploit this emerging paradigm in drug discovery.


A new perspective on the design of molecular therapeutics is emerging This new strategy emphasizes the rational complementation of functionality along extended patches of a protein surface with the aim of inhibiting proteinprotein interactions The successful development of compounds able to inhibit these interactions offers a unique chance to selectively intervene in a large number of key cellular processes related to human diseaseProtein Surface Recognition presents a detailed treatment of this strategy with topics including an extended survey of protein protein interactions that are key players in human disease and biology and the potential for therapeutics derived from this new perspective the fundamental physical issues that surround protein protein interactions that must be considered when designing ligands for protein surfaces examples of protein surface small molecule interactions including treatments of protein natural product interactions protein interface peptides and rational approaches to protein surface recognition from model to biological systems a survey of techniques that will be integral to the discovery of new small molecule protein surface binders from high throughput synthesis and screening techniques to in silico and in vitro methods for the discovery of novel protein ligandsProtein Surface Recognition provides an intellectual tool kit for investigators in medicinal and bioorganic chemistry looking to exploit this emerging paradigm in drug discovery.

Protein Surface Recognition Approaches for Drug Discovery

Protein Surface Recognition Approaches for Drug Discovery

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